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Obagi Tretinoin Gel 0.05% tube

Obagi Tretinoin Gel 0.05%

Fight acne with prescription-strength renewal that feels light on skin.

Tretinoin 0.05% · 20 g branded Obagi gel

  • Helps clear clogged pores and prevent new breakouts
  • Lightweight gel absorbs quickly without a heavy cream feel
  • Supports smoother-looking texture and the appearance of fine lines over time
Is this your first order—or your next one?

Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.

Approval information

If you need new approval, we'll guide you through the questions before your order can ship.

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Clearer pores. Smoother texture. A lighter path to the skin you want.

Obagi Tretinoin Gel product tube01Made for breakout-prone skinThe fast-absorbing gel helps keep pores clear and treats acne without adding the richer feel some oily or combination skin dislikes.
Abstract skin renewal concept02Clearer pores. Smoother texture.Consistent skin renewal helps unclog pores, reduce breakouts, and soften the look of rough texture and post-breakout unevenness.
Established MintRx lifestyle couple sharing a relaxed moment at home03Lightweight enough to stay consistentA quick-absorbing finish makes it easier to keep prescription skin renewal in your nighttime routine.

Why choose gel over cream?

Comparison criteria
Obagi Tretinoin GelObagi Tretinoin GelLightweight acne-focused renewal
Generic Tretinoin CreamGeneric Tretinoin CreamA richer topical format
Breakout-prone skin
Included: Lightweight option for oily or combination skin
Competitor detail: May feel richer on oily skin
Absorption
Included: Fast, light gel finish
Competitor detail: Creamier finish
Pore support
Included: Prescription tretinoin 0.05%
Competitor detail: Depends on strength selected
Texture goals
Included: Breakouts + smoother-looking texture
Competitor detail: Acne and skin renewal support
Best fit
Included: People who do not want a heavy cream
Competitor detail: People who prefer a richer feel

Prescription treatment + a MintRx pharmacist in your corner = support that stays with you.

“If breakouts and clogged pores are the main concern, the Obagi gel is often the better fit for oily or acne-prone skin because it absorbs quickly without the heavier feel of a cream. Start every other night, know that your skin may look a little busier before it looks clearer, and let us help adjust the routine so you do not give up during the early purge.”
Kendall Gordon, MintRx Pharmacist

More ways to build clearer, smoother-looking skin

UltraSkin

estriol + antioxidants + hyaluronic acid

  • Firmness and hydration support
  • Five actives in one cream
  • Retinoid-free nighttime option
$95$85.50/month with Auto Refill
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Firma

GHK-Cu + tretinoin + hydration support

  • Copper peptide + tretinoin
  • Face and neck firmness support
  • Five actives in one pump
From $225/momonthly, quarterly, and one-time options
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Tretinoin Cream

prescription skin renewal

  • Acne and pore support
  • Smoother-looking texture
  • Three available strengths
From $5920 g tube
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Obagi Clear Rx

dark-spot correction

  • Targets stubborn dark spots
  • Branded Obagi treatment
  • Helps improve uneven-looking tone
$13057 g cream
Pricing and safety details

Ready to get more serious about breakouts?

Complete a private online visit and see whether Obagi Tretinoin Gel fits your acne and texture goals.

Start your clearer-skin plan
Important safety information

Obagi Tretinoin Gel 0.05% is an FDA-approved prescription drug for acne vulgaris and is not compounded. Anti-aging use is off-label. Do not use during pregnancy, while planning pregnancy, or while breastfeeding. Apply no more than a pea-sized amount to clean, completely dry skin at bedtime as directed. Avoid the eyes, corners of the nose and mouth, open wounds, sunburn, and active eczema or rosacea flares. Common effects include peeling, dryness, redness, burning, stinging, tightness, increased sun sensitivity, and temporary acne worsening during the first several weeks. Start every other night only if directed, then increase as tolerated. Do not combine with benzoyl peroxide, salicylic acid, strong exfoliants, or other topical medicines unless your provider directs you to. Daily broad-spectrum SPF 30+ is mandatory. Excess application increases irritation and does not improve results. Store at controlled room temperature away from heat and sunlight. Individual results vary, and no guarantee is provided.