
Women's HRT Program
estriol + estradiol cream and micronized progesterone
- One coordinated 90-day treatment
- Day-and-night hormone support
- Pharmacist follow-up built in

Turn down hot flashes. Sleep more comfortably. Feel more like yourself.
Estriol + estradiol cream · micronized progesterone capsules
Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.
If you need new approval, we'll guide you through the questions before your order can ship.
01A simpler path back to feeling like youOne coordinated 90-day program brings estriol and estradiol cream together with provider-selected micronized progesterone around the relief, rest, and comfort you want back.
02Turn down the symptoms disrupting your dayPersonalized estriol and estradiol cream is designed to support relief from hot flashes, night sweats, vaginal discomfort, and the mood and sleep changes that can make this chapter feel unlike you.
03Feel more balanced, day and nightMicronized progesterone completes the hormone plan when prescribed and may support the calmer nighttime routine you have been missing.
Estriol + Estradiol CreamPersonalized estrogen support
Micronized ProgesteroneThe balancing half of the plan“Hormone therapy should not feel like someone handed you a prescription and disappeared. Your morning cream and bedtime progesterone are only the starting point - we check in every three weeks, listen to what is changing with your sleep, mood, hot flashes, and energy, and help adjust the plan until you feel like yourself again.”— Haley Shaffer, MintRx Pharmacist
FEEL MORE LIKE YOU
Start your private online intake and take the first step toward personalized hormone support built around your symptoms and the way you want to feel.
Women's hormone therapy requires individualized benefit-risk review. Do not use during pregnancy. Estrogen-containing therapy and progesterone may be contraindicated with unexplained vaginal bleeding, known or suspected breast cancer or another estrogen-dependent cancer, prior or active blood clots, stroke, heart attack, active liver disease, or ingredient hypersensitivity. Tell your provider about your uterus status, migraine history, cardiovascular risks, gallbladder disease, endometriosis, fibroids, seizure disorders, asthma, diabetes, lupus, all medicines, and family cancer or clotting history. Estrogen therapy can increase risks including blood clots, stroke, heart attack, gallbladder disease, abnormal bleeding, and certain cancers; risks vary by formulation, route, dose, duration, age, and individual history. Progesterone may cause drowsiness, dizziness, headache, breast tenderness, bloating, and mood changes; take it only as directed and use caution with driving until effects are known. Seek urgent help for chest pain, shortness of breath, coughing blood, one-sided leg swelling, sudden severe headache, weakness or numbness, vision or speech change, severe allergic reaction, or suicidal thoughts. Report any new breast change or unexpected vaginal bleeding promptly. Use the lowest effective dose for treatment goals and reassess regularly with the care team. The Bi-Est cream is compounded and not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded medications before marketing. The progesterone capsule is a commercially manufactured FDA-approved generic; review its manufacturer labeling and inactive ingredients with the pharmacist because packaging and excipients may vary. Individual results vary and no symptom outcome is guaranteed.