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MintRx
MintRx estriol and estradiol cream with micronized progesterone

Women's Hormone Therapy

Turn down hot flashes. Sleep more comfortably. Feel more like yourself.

Estriol + estradiol cream · micronized progesterone capsules

  • Built to help ease hot flashes, night sweats, sleep disruption, mood shifts, and vaginal discomfort
  • Estriol, estradiol, and progesterone play complementary roles in one coordinated 90-day program
  • A private online path to personalized treatment without rearranging your life around appointments
Is this your first order—or your next one?

Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.

Approval information

If you need new approval, we'll guide you through the questions before your order can ship.

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LegitScript Certified
LegitScript CertifiedVerified healthcare standards
5-Star Google ReviewsTrusted by MintRx patients
Pharmacists Who CareReal people who listen, answer, and care about you

Get back to feeling steadier, rested, comfortable, and in control.

MintRx Women's HRT program products01A simpler path back to feeling like youOne coordinated 90-day program brings estriol and estradiol cream together with provider-selected micronized progesterone around the relief, rest, and comfort you want back.
Text-free day and night balance concept02Turn down the symptoms disrupting your dayPersonalized estriol and estradiol cream is designed to support relief from hot flashes, night sweats, vaginal discomfort, and the mood and sleep changes that can make this chapter feel unlike you.
MintRx Women's HRT lifestyle model03Feel more balanced, day and nightMicronized progesterone completes the hormone plan when prescribed and may support the calmer nighttime routine you have been missing.

Two strategic roles. One program built to help you feel like yourself again.

Comparison criteria
Estriol + Estradiol CreamPersonalized estrogen support
Micronized ProgesteroneThe balancing half of the plan
Daily-life relief
Included: Targets hot flashes, night sweats, vaginal discomfort, mood and sleep changes
Included: Works alongside estrogen as the balancing half of the plan
Strategic role
Included: Restores estrogen support tied to the symptoms affecting you
Included: Helps protect the uterine lining when prescribed with estrogen
Easy routine
Included: Personalized topical cream
Included: Provider-selected oral capsule
How it may feel
Included: More comfortable days and fewer disruptive symptoms
Included: May support the calmer nighttime routine you have been missing
One coordinated program
Included: Included in your 90-day treatment
Included: Included when prescribed in your 90-day treatment

Prescription treatment + a MintRx pharmacist in your corner = support that stays with you.

“Hormone therapy should not feel like someone handed you a prescription and disappeared. Your morning cream and bedtime progesterone are only the starting point - we check in every three weeks, listen to what is changing with your sleep, mood, hot flashes, and energy, and help adjust the plan until you feel like yourself again.”
Haley Shaffer, MintRx Pharmacist

One complete quarterly HRT program

Women's HRT Program

estriol + estradiol cream and micronized progesterone

  • One coordinated 90-day treatment
  • Day-and-night hormone support
  • Pharmacist follow-up built in
$305quarterly · about $102/month
Pricing and safety details

Move toward cooler days, calmer nights, and more confidence in your body.

Start your private online intake and take the first step toward personalized hormone support built around your symptoms and the way you want to feel.

Start feeling like yourself again
Important safety information

Women's hormone therapy requires individualized benefit-risk review. Do not use during pregnancy. Estrogen-containing therapy and progesterone may be contraindicated with unexplained vaginal bleeding, known or suspected breast cancer or another estrogen-dependent cancer, prior or active blood clots, stroke, heart attack, active liver disease, or ingredient hypersensitivity. Tell your provider about your uterus status, migraine history, cardiovascular risks, gallbladder disease, endometriosis, fibroids, seizure disorders, asthma, diabetes, lupus, all medicines, and family cancer or clotting history. Estrogen therapy can increase risks including blood clots, stroke, heart attack, gallbladder disease, abnormal bleeding, and certain cancers; risks vary by formulation, route, dose, duration, age, and individual history. Progesterone may cause drowsiness, dizziness, headache, breast tenderness, bloating, and mood changes; take it only as directed and use caution with driving until effects are known. Seek urgent help for chest pain, shortness of breath, coughing blood, one-sided leg swelling, sudden severe headache, weakness or numbness, vision or speech change, severe allergic reaction, or suicidal thoughts. Report any new breast change or unexpected vaginal bleeding promptly. Use the lowest effective dose for treatment goals and reassess regularly with the care team. The Bi-Est cream is compounded and not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded medications before marketing. The progesterone capsule is a commercially manufactured FDA-approved generic; review its manufacturer labeling and inactive ingredients with the pharmacist because packaging and excipients may vary. Individual results vary and no symptom outcome is guaranteed.