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Obagi Tretinoin Cream 0.05% tube

Obagi Tretinoin Cream

Clear breakouts. Smooth texture. Reveal fresher-looking skin.

Tretinoin 0.025%, 0.05%, or 0.1% · 20 g branded Obagi cream

  • Helps unclog pores and reduce acne breakouts
  • Supports smoother-looking texture and visible skin renewal
  • Three strengths let you choose the treatment level that fits your routine
Is this your first order—or your next one?

Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.

Approval information

If you need new approval, we'll guide you through the questions before your order can ship.

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Pharmacists Who CareReal people who listen, answer, and care about you

A proven prescription cream for clearer, smoother-looking skin.

Obagi Tretinoin Cream product tube01Three strengths. One clear goal.Choose 0.025%, 0.05%, or 0.1% based on the treatment level you need and the routine you can stay consistent with.
Abstract skin renewal concept02Breakouts and texture in the same routinePrescription skin renewal helps keep pores clear while gradually improving the look of rough texture, fine lines, and uneven skin.
Adult woman with luminous skin holding a skincare dropper03A cream made for consistencyThe cream format gives normal-to-dry skin a more comfortable way to keep tretinoin in the nighttime routine.

Why choose cream over gel?

Comparison criteria
Obagi Tretinoin CreamThree strengths + a cream finish
Obagi Tretinoin GelObagi Tretinoin GelA lighter topical format
Strength choice
Included: 0.025%, 0.05%, or 0.1%
Competitor detail: Often fewer available strengths
Skin feel
Included: Creamy and more cushioning
Competitor detail: Lightweight and fast absorbing
Normal-to-dry skin
Included: Often the more comfortable format
Competitor detail: May feel more drying
Acne support
Included: Prescription-strength pore renewal
Competitor detail: Prescription-strength pore renewal
Long-term texture goals
Included: Built for a consistent nighttime routine
Competitor detail: Also supports skin renewal

Prescription treatment + a MintRx pharmacist in your corner = support that stays with you.

“I always tell people to start tretinoin slowly - every other night for the first week or so gives your skin time to adjust and can help limit irritation. From there, consistency is the key; build it into your nighttime routine and stick with it.”
— Haley Shaffer, MintRx Pharmacist

More ways to build clearer, smoother-looking skin

UltraSkin

estriol + antioxidants + hyaluronic acid

  • Firmness and hydration support
  • Five actives in one cream
  • Retinoid-free nighttime option
$95$85.50/month with Auto Refill
Pricing and safety details

Firma

GHK-Cu + tretinoin + hydration support

  • Copper peptide + tretinoin
  • Face and neck firmness support
  • Five actives in one pump
From $225per month · monthly, quarterly, and one-time options
Pricing and safety details

Obagi Clear Rx

prescription dark-spot correction for uneven tone

  • Targets stubborn dark spots
  • Branded Obagi treatment
  • Helps improve uneven-looking tone
$13057 g cream
Pricing and safety details

Choose a tretinoin routine you can stick with.

Complete a private online visit and see whether Obagi Tretinoin Cream fits your acne, texture, and renewal goals.

Start your skin-renewal plan
Important safety information

Obagi Tretinoin Cream is an FDA-approved prescription drug for acne vulgaris and is not compounded. Anti-aging use is off-label. Do not use during pregnancy, while planning pregnancy, or while breastfeeding. Apply no more than a pea-sized amount to clean, completely dry skin at bedtime as directed. Avoid the eyes, corners of the nose and mouth, open wounds, sunburn, and active eczema or rosacea flares. Peeling, dryness, redness, burning, stinging, tightness, increased sun sensitivity, and temporary acne worsening are common during adjustment. Do not combine with benzoyl peroxide, salicylic acid, strong exfoliants, or other topical medicines unless directed. Daily broad-spectrum SPF 30+ is mandatory. Excess application increases irritation and does not improve results. Store at controlled room temperature away from heat and sunlight. Individual results vary.