
UltraSkin
estriol + antioxidants + hyaluronic acid
- Firmness and hydration support
- Five actives in one cream
- Retinoid-free nighttime option

Fade stubborn dark spots and bring back a more even-looking tone.
Hydroquinone 4% · 2 oz / 57 g
Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.
If you need new approval, we'll guide you through the questions before your order can ship.
01Go after stubborn spotsBuilt for dark spots, melasma, sun damage, age spots, and post-acne marks that keep your tone from looking even.
02Turn down excess pigment at the sourceThe prescription formula helps reduce new pigment formation while your normal skin renewal gradually clears visible discoloration.
03A brighter-looking complexion, not another guessA defined treatment plan gives stubborn discoloration a more focused approach than adding another cosmetic serum to the shelf.
Obagi Clear RxBranded dark-spot treatmentBoth are prescription hydroquinone options. Clear Rx adds Obagi brand consistency and Nu-Derm routine compatibility.
“Clear Rx is the step up when the OTC brighteners have had months and the same dark spots are still there. Use a thin layer only where you need it, make sunscreen non-negotiable, and let us help map out the treatment and off-cycle so the prescription-strength 4% hydroquinone works as hard as it should.”— Nathan Parker, MintRx Pharmacist
MAKE DARK SPOTS LESS NOTICEABLE
Complete a private online visit and see whether Clear Rx fits your discoloration and tone goals.
Clear Rx contains prescription hydroquinone 4% and is not compounded. Do not use during pregnancy or breastfeeding. Do not use on broken, sunburned, or irritated skin or with known hydroquinone, sulfite, or ingredient allergy. Apply a thin layer only to affected areas as prescribed and avoid eyes and lips. Daily broad-spectrum SPF 30+ is mandatory during treatment and afterward. Limit treatment to 3–6 months followed by at least 3 months off. Continuous use can cause exogenous ochronosis, a potentially permanent paradoxical darkening; patients with very dark skin tones require close provider supervision. Stinging, burning, redness, dryness, peeling, irritation, or rare allergic reaction may occur. Keep tightly closed at room temperature away from heat and light. Individual results vary.