
Tretinoin
prescription cream for acne, texture, and tone
- Acne and pore support
- Smoother-looking texture
- Three available strengths

Fade stubborn discoloration and level up your nighttime renewal routine.
Hydroquinone 4% · 2 oz / 57 g
Starting this treatment? We’ll guide you through the health questions. Already approved? Choose your next quantity without starting over.
If you need new approval, we'll guide you through the questions before your order can ship.
01Make stubborn spots less noticeableGive melasma, sun spots, age spots, and post-acne marks a prescription fading treatment built around a clearer, more even-looking complexion.
02Fade and renew in the same nighttime routineWhen directed, pair Blender Rx with tretinoin so dark-spot correction and skin renewal work toward the same brighter-looking goal.
03Build toward clearer, brighter-looking skinReplace a shelf of guesses with one focused Obagi plan for discoloration, texture, and the more even-looking tone you want to see.
Obagi Blender RxMade for a nighttime renewal pairing
Generic Hydroquinone CreamStandalone fading treatment“Blender Rx is not just another hydroquinone cream - its best trick is how well it pairs with tretinoin. Mixing a pea-sized amount of each in your palm is the classic Obagi nighttime routine for stubborn pigmentation; let us help you start at the right frequency and adjust the routine if your skin gets too dry.”— Kendall Gordon, MintRx Pharmacist
FADE + RENEW
Start a private online visit and see whether Blender Rx fits the tone, texture, and dark-spot goals you want your nighttime routine to deliver.
Blender Rx contains prescription hydroquinone 4% and is not compounded. Do not use during pregnancy or breastfeeding. Do not use on broken, sunburned, or irritated skin or with known hydroquinone, sulfite, or ingredient allergy. Apply only as prescribed. Do not mix with tretinoin unless your provider specifically directs the amount and frequency. Daily broad-spectrum SPF 30+ is mandatory. Limit treatment to 3–6 months followed by at least 3 months off. Continuous use can cause exogenous ochronosis, a potentially permanent paradoxical darkening; patients with very dark skin tones require close provider supervision. Stinging, burning, redness, dryness, peeling, irritation, or rare allergic reaction may occur. Keep tightly closed at room temperature away from heat and light. Individual results vary.