Velora is a once-daily compounded oral capsule combining Bupropion, Naltrexone, and Topiramate — three prescription actives designed to target three different appetite and reward pathways in the brain.
Built as a structured 3-month titration program followed by simple twice-daily maintenance. Compounded fresh in a U.S.-based licensed pharmacy in vegan vegetable capsules.
Titration Program $295 · 3-Month Supply
Free online visit · One consult covers your entire journey · Cancel anytime

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Velora is built on the principle that overeating is driven by more than one system. Bupropion + Naltrexone target the homeostatic "I'm hungry" drive. Topiramate layers on the reward and satiety arm — together in a single compounded oral capsule.

A norepinephrine-dopamine reuptake inhibitor that stimulates POMC neurons in the hypothalamus to release α-MSH — an anorectic signal designed to help reduce between-meal hunger and support energy and focus.

Blocks the β-endorphin autoinhibitory feedback loop on POMC neurons — designed to sustain bupropion's appetite-suppressing signal instead of letting it self-limit.

Adds an independent reward-and-satiety mechanism — designed to dampen GABA-driven food reward, lower leptin resistance, and help quiet "food noise" beyond simple hunger.
Velora is not Contrave (bupropion + naltrexone only) and not Qsymia or Bella (which contain phentermine, a Schedule IV controlled substance). Velora deliberately contains no phentermine.
Answer a few confidential questions about your health and weight-loss goals. It only takes a few minutes.
A licensed provider reviews your profile and writes your Velora prescription if appropriate. One consult covers your entire journey.
Velora is compounded to order in a U.S.-based licensed pharmacy in vegan vegetable capsules.
Discreet shipping via UPS Ground. Right to your door — every month during titration, every 90 days on maintenance.
Velora is an oral capsule — a non-injectable alternative for patients who prefer to skip weekly self-injections.
Unlike Qsymia or Bella, Velora deliberately omits phentermine. All three actives are prescription-only but none are scheduled.
Bupropion + Naltrexone target homeostatic appetite. Topiramate adds reward and satiety. Three distinct pathways, one capsule.
A single free telehealth consult covers the entire 3-month titration program and your subsequent maintenance refills — no per-refill consult fees.
Plant-derived HPMC capsules instead of gelatin — suitable for vegan, vegetarian, kosher, and halal patients without disclosure carve-outs.
Direct phone access and a free 15-minute consult with a licensed pharmacist — anytime you have a question about your dosing or side effects.

Overeating isn't a single-pathway problem. Velora is designed to address three at once — homeostatic hunger, sustained appetite suppression, and reward-driven eating.
Bupropion-driven POMC activation, sustained by naltrexone, is designed to reduce between-meal hunger so smaller portions feel "enough."
Topiramate adds a reward-and-satiety mechanism designed to dampen cravings and reduce reward-driven snacking — especially evenings and sweets.
A structured 3-month titration ramps your dose gradually to help manage side effects, then transitions to a simple twice-daily maintenance capsule.
Oral once- or twice-daily dosing. No needles, no cold storage, no weekly injection routine.

Weeks 1–2: Mild appetite reduction begins; possible adjustment-phase nausea or dry mouth, generally subsides within 7–10 days

Weeks 3–4: More consistent reduction in between-meal hunger; cravings noticeably softer; early scale movement for most patients

Weeks 5–8: Weight loss may accelerate as titration deepens; satiety per meal increases

Weeks 9–12: Full titration reached; cumulative loss in clinical literature on individual ingredients typically ranges 4–8% of starting body weight

Month 4+: Steady-state maintenance dose — one capsule twice daily; weight loss continues at a slower, sustainable pace
Individual results may vary. Timeline and percentages are extrapolated from published research on the individual active ingredients and on the FDA-approved bupropion + naltrexone combination — Velora as a 3-ingredient compounded combination has not been evaluated in clinical trials.
Pharmacist-led care. That means we control quality, speed, and your experience from start to finish.

Hand off to partner pharmacies

A U.S.-based pharmacy compounds your medication

Round-robin customer service

One agent owns your case

Automated responses

Immediate pharmacist access

Per-refill consult fees

One consult covers your entire journey

Generic packaging

Discreet branded packaging — no weight-loss callouts on the outside
Free online visit. Compounded fresh in a U.S.-based licensed pharmacy. Delivered discreetly to your door.
Titration Program $295 (3-Month Supply)
Maintenance $295 every 90 days · Auto Refill $265.50 (save 10%) · Cancel anytime
Get StartedVelora is a compounded prescription medication. Compounded medications are not FDA-approved. The FDA does not verify the safety, effectiveness, or quality of compounded medications before they are marketed. Active pharmaceutical ingredients are sourced from FDA-registered facilities. Not for use during pregnancy or while nursing. Individual results may vary.