FIRMA is built around GHK-Cu — a naturally occurring copper tripeptide first identified in human plasma in 1973 and studied for decades for its role in collagen and elastin signaling. As we age, GHK-Cu levels in the skin drop sharply, which may contribute to the visible laxity that shows up earliest on the neck, jawline, and chest.
FIRMA pairs prescription-strength GHK-Cu 0.5% with four supporting actives — Tretinoin, Hyaluronic Acid, Vitamin C, and Niacinamide — in a single cream compounded fresh in a U.S.-based licensed pharmacy.
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FIRMA addresses how skin actually ages — through five distinct biological pathways that researchers have studied for decades.
A copper peptide that may help support the skin's natural collagen and elastin production signals.
Prescription-strength retinoid with 40+ years of clinical use — supports cell turnover and collagen production.
Holds up to 1,000x its weight in water. Helps replenish hydration and may help improve skin texture.
A potent antioxidant and essential cofactor for collagen synthesis. May help brighten and even skin tone.
Supports the skin barrier and ceramide production. May help reduce visible redness and uneven texture.
Answer a few confidential questions about your skin goals. It only takes a few minutes.
A licensed provider reviews your skin profile and recommends the right formula for you.
Your FIRMA cream is compounded fresh in a U.S.-based licensed pharmacy — made to order just for you.
Free discreet shipping. Right to your door.
Forget the 6 serums and 10-step layering. FIRMA delivers five prescription-strength actives in one easy application.
OTC creams use trace amounts of actives. FIRMA uses prescription concentrations formulated by licensed providers.
Repair signaling, cell turnover, deep hydration, antioxidant defense, and barrier support — all in one cream.
Not mass-produced. Each FIRMA prescription is compounded fresh in a U.S.-based licensed pharmacy.
Direct phone access and a free 15-minute consult with a licensed pharmacist — included with your purchase.

Skin aging isn't a single-pathway problem. FIRMA is designed to address five key mechanisms that contribute to visible aging — in one convenient formula.
GHK-Cu (copper tripeptide) is designed to support the skin's natural collagen and elastin production signals.
Prescription-strength Tretinoin 0.025% supports cell turnover and may help improve skin texture over time.
Hyaluronic Acid holds up to 1,000x its weight in water — helping replenish hydration and improve skin texture.
Vitamin C (5% L-ascorbic acid) helps neutralize environmental stress and is a key cofactor for collagen synthesis.
Niacinamide 5% supports the skin barrier and may help reduce visible redness and irritation.

Week 1: Skin may feel plumper, smoother, and more hydrated

Weeks 1–4: Possible adjustment period — mild dryness or flaking from Tretinoin is normal

Weeks 4–8: Surface texture and tone improvements may begin to appear

Weeks 8–12: Visible firming and improved tone may become noticeable with consistent use

Daily broad-spectrum SPF 30+ is required throughout treatment
Individual results may vary.
Pharmacist-led care. That means we control quality, speed, and your experience from start to finish.
Hand off to partner pharmacies
A U.S.-based pharmacy compounds your medication
Round-robin customer service
One agent owns your case
Automated responses
Immediate pharmacist access
Wait for complaints
Proactive 14-day check-in calls
Generic packaging
Custom branding, from box to thank-you card
FIRMA is a prescription-strength skincare cream that combines five clinically-studied actives — GHK-Cu, Tretinoin, Hyaluronic Acid, Vitamin C, and Niacinamide — in a single formula designed to address visible signs of aging on the neck, face, and chest.
Unlike over-the-counter products that use trace amounts of actives, FIRMA contains prescription-strength concentrations compounded fresh by a licensed U.S. pharmacy. This allows for more targeted support of collagen and elastin production.
Apply a small amount to clean, dry skin once daily in the evening. Start with every other day for the first two weeks, then increase to nightly use as tolerated. Always use SPF 30+ during the day.
Many patients notice improved hydration and texture within the first few weeks. More visible firming and tone improvements typically become noticeable around weeks 8–12 with consistent use.
Some patients may experience mild dryness, flaking, or sensitivity during the first few weeks — this is normal as skin adjusts to Tretinoin. These effects typically subside with continued use.
FIRMA is not recommended for pregnant or nursing women, or those with known allergies to any of the ingredients. Consult your provider if you have sensitive skin conditions like rosacea or eczema.
Yes, FIRMA requires a prescription. Our online consultation process connects you with a licensed provider who reviews your skin profile and determines if FIRMA is right for you — all included in your purchase.
Your complete formula is $295. This includes the prescription cream, provider consultation, pharmacist access, and free discreet shipping.
If you're not satisfied with your purchase, please contact our support team within 30 days. We're committed to ensuring you have a positive experience with FIRMA.
FIRMA is a compounded medication prepared by a licensed U.S. pharmacy. While the individual ingredients are FDA-approved, compounded formulas are not FDA-approved as they are customized prescriptions.
Free online visit. Compounded fresh in a U.S.-based licensed pharmacy. Delivered discreetly to your door.